About Does Cbd Get You High? - Bestcbdoil.com It likewise binds to cannabinoid 2 (CB2) receptors located in the brainstem and hippocampus, which has links to memory and feelings. Immune cells, bone cells, and spleen and liver cells also consist of CB2 receptors. This prevalent distribution of cannabinoid receptors is the reason that THC produces such powerful physical and mental effects. CBD does not bind to either CB1 or CB2 receptors. According to a 2018 review article, CBD may lower the ability of THC and other cannabinoids to bind to the CB1 receptor's. This may minimize the psychedelic results of THC and might increase the variety of distributing cannabinoids. A 2018 review in Surgical Neurology International indicates that CBD might reduce inflammation in the brain by simply click the following internet site indirectly communicating with CB2 receptors. Anecdotal evidence and initial research study suggest that CBD might assist treat a variety of conditions, including: